TGFbeta1 Antilichaam [4F9C10]

TGF beta (transforming growth factor beta), with 390-amino acid protein (about 43 kDa), is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. In mammals, three isoforms of TGFbeta, that is, beta1, beta2, and beta3, are known. TGF beta is one of numerous inhibitory factors produced by cancer cells that regulate antitumor immunity. TGF beta1 takes part in the local response in the course of primary lung cancer and TGFbeta1 is thought to be implicated in breast cancer progression.TGFbeta1 also plays a critical role in the downregulation of microglial responses minimizing brain inflammation and thus avoiding exacerbation of brain damage.

7040

P01137

P01137

Human

Ni-NTA purified truncated recombinant TGFbeta1 expressed in E. Coli strain BL21 (DE3) .

4F9C10

Unconjugated

Primary Antibodies

Growth Factors, Growth Factors

Batch dependent

Ascitic fluid containing 0.03% sodium azide.

None

Blue Ice

TGF beta1 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG2a

TGFB1

Transforming growth factor, beta 1

Homo sapiens

Delphine Boche, Colm Cunningham, Fabian Docagne. Neurobiol Dis. 2006 Feb 27

Shizuya Saika. Lab Invest. 2006 Feb;86 (2) :106-15

TGFBTGF-beta-1, CED, LAP, DPD1, TGFB, TGFbeta

ELISA, WB

135674