TGFBR1 Antilichaam

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS) . Multiple transcript variants encoding different isoforms have been found for this gene.

7046

P36897

Human, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 34-124 of human TGFBR1 (NP_001124388.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Growth Factors, Signal Transduction, Stem Cell

Affinity purification

HepG2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 56kDa

IgG

TGFBR1

HeLa

PC-3

Transforming growth factor, beta receptor 1

Homo sapiens

Activin A receptor type II-like kinase, 53kD, TGF-beta type I receptor, TGF-beta receptor type-1, TGF-beta receptor type I, TGFR-1, SKR4, LDS2A, LDS1A, ALK5, ALK-5, ACVRLK4, AAT5, transforming growth factor, beta receptor 1, TGFBR1, transforming growth factor-beta receptor type I, beta receptor I (activin A receptor type II-like kinase, 53kD), transforming growth factor beta receptor I, tbetaR-I, serine/threonine-protein kinase receptor R4, activin receptor-like kinase 5, activin A receptor type II-like kinase, 53kDa

WB, IHC, IF

Liquid