TGM7 Antilichaam

TGM7 Antibody: Transglutaminases (TGM) are a family of structurally and functionally related Ca2+-dependent enzymes (TGases) that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. TGases influence numerous biological processes, including blood coagulation, cell differentiation, fertilization and apoptosis. TGM7 belongs to the transglutaminase superfamily and is also thought to catalyze the cross-linking of proteins, often resulting in stabilization of protein assemblies. Little is known of the role of TGM7, but defects in the highly related protein TGM5 are associated with acral peeling skin syndrome.

116179

Q96PF1

AF363393

Human, Mouse

Unconjugated

Primary Antibodies

Apoptosis

TGM7 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1302 - Human Lung Tissue Lysate

1 mg/mL

TGM7 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

TGM7 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

TGM7 antibody is predicted to not cross-react with other TGase protein family members. At least two isoforms of TGM7 are known to exist; this antibody will recognize both isoforms.

TGM7

Cat. No. 17-003 - A549 Cell Slide

Transglutaminase 7

Homo sapiens

Ueki S, et al. Dual functions of transglutaminase in novel cell adhesion. J. Cell Sci. 1996; 109:2727-35

Grenard P, Bates MK, and Aeschlimann D. Evolution of transglutaminase genes: identification of a transglutaminase gene cluster on human chromosome 15q15. J. Biol. Chem. 2001; 276:33066-78.

Cassidy AJ, van Steensel MA, Steijlen PM, et al. A homozygous missense mutation in TGM7 abolishes epidermal transglutaminase 5 activity and causes acral peeling skin syndrome. Am. J. Hum. Genet. 2005; 77:909-17.

TGM7 Antibody: TGMZ, Protein-glutamine gamma-glutamyltransferase Z, Transglutaminase Z, TGZ

ELISA, WB, ICC, IF

16445035

Liquid