TGN-073

TGN-073 is a facilitator of aquaporin-4 (AQP4), an astroglial water channel. TGN-073 reveals an increase of up to 41% in glymphatic transport in rat brain[1].

877459-36-4

12352005

H302, H315, H319, H335

Aquaporin

Membrane Transporter/Ion Channel

Neuroscience-Neuromodulation

Neurological Disease

99.53

O=S(C1=CC=CC=C1)(NC2=NC=CC=C2OCC3=CC=CC=C3)=O

C18H16N2O3S

340.40

H302, H315, H319, H335

[1]Alaa Alghanimy, et al. The effect of a novel AQP4 facilitator, TGN-073, on glymphatic transport captured by diffusion MRI and DCE-MRI. PLoS One. 2023 Mar 15;18 (3) :e0282955.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-W176557/TGN-073-SDS-MedChemExpress.pdf

Reference compound1

No Development Reported