Thalidomide-5-F-6-azetidine-MeOH
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Thalidomide-5-F-6-azetidin-MeOH is a synthesized E3 ligase ligand-linker conjugate that can be used for synthesis of PROTAC FLT3/CHK1 Degrader-1. PROTAC FLT3/CHK1 Degrader-1 is a potent FLT3/CHK1 degrader with anti-tumor activity[1].
2934621-29-9
12352005
E3 Ligase Ligand-Linker Conjugates
PROTAC
Cancer
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=C(N4CC(CO)C4)C(F)=C3)=O
C17H16FN3O5
361.32
[1]Lian X, et al. Development of Dual FLT3 and CHK1 PROTACs for the Treatment of AML. J Med Chem. 2025 Oct 23;68 (20) :21939-21961.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W998238/
Reference compound1
No Development Reported
Beschrijving
Thalidomide-5-F-6-azetidin-MeOH is a synthesized E3 ligase ligand-linker conjugate that can be used for synthesis of PROTAC FLT3/CHK1 Degrader-1. PROTAC FLT3/CH
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