Thalidomide-O-PNB-ester
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Thalidomide-O-PNB ester is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-O-PNB ester can be linked to a target protein ligand via a linker to form a PROTAC.
12352005
Ligands for E3 Ligase
PROTAC
Cancer
O=C1CCC(C(N1)=O)N2C(C3=C(C(OCC(OC4=CC=C([N+]([O-])=O)C=C4)=O)=CC=C3)C2=O)=O
C21H15N3O9
453.36
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W1130334/
Reference compound1
No Development Reported
Cereblon
Beschrijving
Thalidomide-O-PNB ester is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-O-PNB ester can be linked to a target
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