Thalidomide-pyrazole
Gecertificeerd

Thalidomide-pyrazole

Catalog #: HY-W248665
Maat: 1 Each

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
Login voor prijs
BTW niet inbegrepen
Gratis verzending vanaf €100

Technische Specificaties

Description

Thalidomide-pyrrolidine is an E3 ligase ligand. Thalidomide-pyrrolidine can be used for synthesis of PROTAC ARD-1676.

CAS Number

2616540-83-9

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Others

Smiles

O=C1NC(C(CC1)N2C(C3=C(C2=O)C=C(CNC4)C4=C3)=O)=O

Molecular Formula

C15H13N3O4

Molecular Weight

299.28

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Xiang W, et al. Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer. J Med Chem. 2023 Sep 28;66 (18) :13280-13303.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W248665/

Scientific Category

Reference compound2

Clinical Information

No Development Reported

Beschrijving

Thalidomide-pyrrolidine is an E3 ligase ligand. Thalidomide-pyrrolidine can be used for synthesis of PROTAC ARD-1676.

Specificaties

ProductnaamThalidomide-pyrazole
Categorie
Beschikbare grootte1 Each
CatalogusnummerHY-W248665