
Thalidomide-pyrazole
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Thalidomide-pyrrolidine is an E3 ligase ligand. Thalidomide-pyrrolidine can be used for synthesis of PROTAC ARD-1676.
2616540-83-9
12352005
H302-H315-H319
Ligands for E3 Ligase
PROTAC
Others
O=C1NC(C(CC1)N2C(C3=C(C2=O)C=C(CNC4)C4=C3)=O)=O
C15H13N3O4
299.28
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
[1]Xiang W, et al. Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer. J Med Chem. 2023 Sep 28;66 (18) :13280-13303.
Room Temperature
-20°C, 3 years; 4°C, 2 years (Powder)
http://file.medchemexpress.com/batch_PDF/HY-W248665/
Reference compound2
No Development Reported
Beschrijving
Thalidomide-pyrrolidine is an E3 ligase ligand. Thalidomide-pyrrolidine can be used for synthesis of PROTAC ARD-1676.
Specificaties
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