Thycine-15N2,13C
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Thymine-15N2,13C is the 13C and 15N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-Fluorouracil (HY-90006) in cancer treatment, with a Km of 2.3 μM[1].
12352005
H319
Endogenous Metabolite; Isotope-Labeled Compounds
Metabolic Enzyme/Protease; Others
Cancer
99.90
O=C([15N](C1=O)[H])C([13CH3])=C[15N]1[H]
C4 13CH6 15N2O2
129.09
H319
[1]Tuchman M, et al. Effects of uridine and thymidine on the degradation of 5-fluorouracil, uracil, and thymine by rat liver dihydropyrimidine dehydrogenase. Cancer Res. 1985 Nov;45 (11 Pt 1) :5553-6.
Room Temperature
-20°C, 3 years; 4°C, 2 years (Powder)
http://file.medchemexpress.com/batch_PDF/HY-W747214/Thymine-15N2-13C-SDS-MedChemExpress.pdf
Isotope-Labeled Compounds
No Development Reported
Beschrijving
Thymine-15N2,13C is the 13C and 15N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-Fluo
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