TIA1 Antilichaam

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly (A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.

7072

P31483

Human, Mouse

A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human TIA1 (NP_071505.2) .

Unconjugated

Primary Antibodies

Apoptosis, Cell Cycle, Immunology

Affinity purification

BT-474

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 43-50kDa

IgG

TIA1

Raji

Mouse brain

Mouse spleen

TIA1 cytotoxic granule-associated RNA binding protein

Homo sapiens

TIA1, WDM, TIA-1

WB, IHC, IF

Liquid