Tiagabine-d4
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Tiagabine-d4 (NO050328-d4) is deuterium labeled Tiagabine. Tiagabine (NO050328) is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC50s of 67, 446 and 182 nM for [3H]GABA uptake in Synaptosomes, Neurons and Glia, respectively[1].
NO050328-d4; NO328-d4; TGB-d4
12352005
Isotope-Labeled Compounds
Others
Neuroscience-Neuromodulation
Neurological Disease
O=C(C1C([2H])N(C([2H])C([2H])C1[2H])CC/C=C(C2=C(C)C=CS2)/C3=C(C)C=CS3)O
C20H21D4NO2S2
379.57
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-B0696S1/
Isotope-Labeled Compounds
No Development Reported
Beschrijving
Tiagabine-d4 (NO050328-d4) is deuterium labeled Tiagabine. Tiagabine (NO050328) is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant age
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