TICRR Antilichaam

TopBP1-interacting checkpoint and replication regulator, Treslin, chromosome 15 open reading frame 42, C15ORF42

90381

Q7Z2Z1

NP_689472

Human

Unconjugated

Primary Antibodies

Cell Cycle

TICRR antibody is affinity chromatography purified via peptide column.

Cat. No. 1308 - Human Small Intestine Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Mouse: (74%)

TICRR antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

TICRR antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

TICRR antibody is human specific. At least two isoforms of TICRR are known to exist.

TICRR

Cat. No. 11-801 - Human Small Intestine Tissue Slide

TOPBP1-interacting checkpoint and replication regulator

Homo sapiens

Sansam CL, Cruz NM, Danielian PS, et al. A vertebrate gene, ticrr, is an essential checkpoint and replication regulator. Genes Dev. 2010; 24:183-94.

Kumagai A, Shevchenko A, Shevchenko A, et al. Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication. J. Cell Biol. 2011;193:995-1007.

Kumagai A, Shevchenko A, Shevchenko A, et al. Treslin collaborates with TopBP1 in triggering the initiation of DNA replication. Cell 2010; 140:349-59.

Mueller AC, Keaton MA, and Dutta A. DNA replication: mammalian Treslin-TopBP1 interaction mirrors yeast Sld3-Dpb11. Curr. Biol. 2011; 21:R638-40.

TICRR Antibody: SLD3, Treslin, C15orf42, TopBP1-interacting checkpoint and replication regulator

ELISA, WB, IHC-P, IF

118421085

Liquid