TIE2 R849W Recombinant humaan actief eiwit Kinase

TIE2 plays an important role in vascular formation and maintenance. Mutations in TIE2 lead to vascular malformations, which are painful vascular lesions that cause disfigurement, bleeding, and thrombosis. TIE2 R849W is the most common mutation implicated in an inherited form of vascular malformations. TIE2 R849W Recombinant Human Active Protein Kinase is a recombinant TIE2 R849W protein that can be used to study TIE2 R849W-related functions[1].

12352211

Tie

Protein Tyrosine Kinase/RTK

Cardiovascular Disease

[TIE2R849WRecombinantHumanActiveProteinKinase]

[1]Kennedy MA, et al. A Tie2 kinase mutation causing venous malformations increases phosphorylation rates and enhances cooperativity. Biochem Biophys Res Commun. 2019 Feb 19;509 (4) :898-902.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-E70782/

Enzyme

No Development Reported