
TIE2 Y1108F Recombinant humaan actief eiwit Kinase
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
TIE2 plays an important role in vascular formation and maintenance. Mutations in TIE2 lead to vascular malformations, which are painful vascular lesions that cause disfigurement, bleeding, and thrombosis. TIE2 Y1108F is the most mutation of TIE2. TIE2 Y1108F Recombinant Human Active Protein Kinase is a recombinant TIE2 Y1108F protein that can be used to study TIE2 Y1108F-related functions[1].
12352211
Tie
Protein Tyrosine Kinase/RTK
Cardiovascular Disease
[TIE2Y1108FRecombinantHumanActiveProteinKinase]
[1]Kennedy MA, et al. A Tie2 kinase mutation causing venous malformations increases phosphorylation rates and enhances cooperativity. Biochem Biophys Res Commun. 2019 Feb 19;509 (4) :898-902.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-E70783/
Enzyme
No Development Reported
Beschrijving
TIE2 plays an important role in vascular formation and maintenance. Mutations in TIE2 lead to vascular malformations, which are painful vascular lesions that ca
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