TIM14-eiwit, S. cerevisiae, Recombinant
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Mitochondrial import inner membrane translocase subunit TIM14 (TIM14) is an essential component of the PAM complex. PAM complex is required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, TIM14 is required to stimulate activity of mtHSP70 (SSC1) . TIM14 belongs to the DnaJ family, which has been involved in Hsp40/Hsp70 chaperone systems. As a mitochondrial chaperone, TIM14 functions as part of the TIM23 complex import motor to facilitate the import of nuclear-encoded proteins into the mitochondria. TIM14 also complexes with prohibitin complexes to regulate mitochondrial morphogenesis, and has been implicated in dilated cardiomyopathy with ataxia.
Ice Packs
-20°C
Beschrijving
TIM14-eiwit, S. cerevisiae, Recombinant Beschikbaar in 5 µg. Bestel eenvoudig online met snelle levering.
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