TIMP-1 Recombinant eiwit

TIMP1 is an extracellular inhibitor of MMPs (see above) including MMP1, 2, 3, 7, 8, 9, 10, 11, 12, 13, and 16. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP1 can also act through an MMP-independent mechanism to promote erythropoiesis by stimulating proliferation and differentiation of erythroid progenitors. Recombinant human TIMP-1 is a 20.6 kDa protein containing 184 amino acid residues.

7076

P01033

NP_003245.1

Recombinant Proteins

E. coli

Cancer, Cell Cycle, Signal Transduction

Room Temp

The lyophilized TIMP-1 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted TIMP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing TIMP-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

TIMP metallopeptidase inhibitor 1

Homo sapiens

EPA, EPO, HCI, CLGI, TIMP, Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA

Human

4507509

Lyophilized