TIMP-2 Recombinant eiwit

TIMP-2 is an extracellular inhibitor of MMPs including MMP1, 2, 3, 7, 8, 9, 10, 12, 13, 14, 15, 16 and 19. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP-2 can also act through an MMP-independent mechanism inhibiting endothelial cell proliferation in vitro and demonstrates anti-angiogenic activities in vivo. Recombinant human TIMP-2 is a 21.8 kDa protein containing 194 amino acid residues.

7077

P16035

NP_003246.1

Recombinant Proteins

E. coli

Signal Transduction, Other

Room Temp

The lyophilized TIMP-2 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted TIMP-2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing TIMP-2 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

TIMP metallopeptidase inhibitor 2

Homo sapiens

DDC8, CSC-21K, Metalloproteinase inhibitor 2, TIMP-2

Human

4507511

Lyophilized