TIMP1 Antilichaam

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.

7076

P01033

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 24-207 of human TIMP1 (NP_003245.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Immunology, Signal Transduction

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 28kDa

IgG

TIMP1

SKOV3

HT-29

Mouse lung

TIMP metallopeptidase inhibitor 1

Homo sapiens

EPA, EPO, HCI, CLGI, TIMP, Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA

WB, IF

Liquid