TIMP2 Antilichaam

This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

7077

P16035

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TIMP2 (NP_003246.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Signal Transduction

Affinity purification

Mouse brain

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 26kDa

IgG

TIMP2

Rat heart

TIMP metallopeptidase inhibitor 2

Homo sapiens

TIMP2, Metalloproteinase inhibitor 2, TIMP-2, CSC-21K

WB, IHC

Liquid