TIMP2 Mouse Monoclonal Antibody [Kloon ID: LBI1B11]

This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq]

Carrier-free (BSA/glycerol-free) TIMP2 mouse monoclonal antibody, clone LBI1B11

CSC-21K; DDC8

Homo sapiens TIMP metallopeptidase inhibitor 2 (TIMP2), mRNA.

7077

P16035

Unconjugated

WB 1:2000, IHC 1:150, FLOW 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Secreted Protein

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

TIMP2

https://www.ncbi.nlm.nih.gov/gene/?term=7077

https://www.uniprot.org/uniprot/P16035