Tinf2 Antilichaam - middengebied HRP (ARP58338_P050-HRP)

TERF1 (TRF1) -interacting nuclear factor 2

TIN2, DKCA3

26277

Q9BSI4

NP_001092744

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig

The immunogen is a synthetic peptide directed towards the middle region of human TINF2

TINF2 is a component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. It plays a role in shelterin complex assembly.

ACD; TERF2; TPP1; ANXA8L1; TNKS; TERF1; VIPR1; ZNF790; PAGE2; TUBB; DHFRL1; APOBEC3F; REM2; NUDCD2; CCDC43; SCRN2; TRIM15; TXNDC17; AFAP1L2; FERMT3; KCTD17; ANKMY2; PPP6R3; PGM2; APPL2; BIN2; LGALSL; PHPT1; GNMT; OR2H1; CCDC9; POT1; AIPL1; NCDN; ACOT7; TO

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

TINF2 is supported by BioGPS gene expression data to be expressed in MCF7

0.5 mg/ml

Cow: 100%; Dog: 86%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 100%; Rat: 85%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

50kDa

Kim, S.H., (2008) J. Cell Biol. 181 (3), 447-460

Wet Ice

451

TINF2

TINF2

Rabbit

TERF1-interacting nuclear factor 2

NM_001099274

SDEEENGQGEGKESLENYQKTKFDTLIPTLCEYLPPSGHGAIPVSSCDCR