Tip60 (fosfo Ser90) Antilichaam

The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.

10524

Q92993

NP_006379.2

Human, Mouse, Rat

Tip60 (phospho Ser90) antibody was raised against a peptide sequence around phosphorylation site of Serine 90 (P-G-S (p) -P-E) derived from Human Tip60.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

58 kDa

IgG

The antibody detects endogenous levels of Tip60 only when phosphorylated at serine 90.

KAT5

K (lysine) acetyltransferase 5

Homo sapiens

Kamine J., Virology 216:357-366 (1996) .

Sheridan A.M., Mol. Cell. Biol. 21:4470-4481 (2001) .

Legube G., Gene 310:161-168 (2003) .

HTATIP, TI60, Tat-interactive protein-60

IHC

36287069

Liquid