Tkip
Gecertificeerd

Tkip

Catalog #: TP2958-01
Maat: 10 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

CAS Number

716361-65-8

Target

JAK, MHC

Related Pathways

Chromatin/Epigenetic, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Stem Cells, Immunology/Inflammation

Bioactivity

Tkip is a specific inhibitor of JAK2. It binds to the autophosphorylation site of JAK2, thereby inhibiting JAK2 autophosphorylation and the phosphorylation of the IFN-γ receptor subunit IFNGR-1. Tkip can suppress the antiviral activity of IFN-γ and the expression of MHC class I molecules. Tkip is applicable in studies related to the IFN-γ signaling pathway.

Smiles

C([C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CC=C(O)C=C4)C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CC6=CC=CC=C6)C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)=O)=O)=O)=O)[C@H](CC)C)=O)C(C)C)=O)=O)=O)[C@H](C)C)=O)CC(C)C)=O)N)C=7C=8C(NC7)=CC=CC8

Molecular Formula

C93H118N16O14

Molecular Weight

1684.03

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Beschrijving

Tkip Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamTkip
Categorie
Beschikbare grootte10 mg
CatalogusnummerTP2958-01