TLR11 Antilichaam

TLR11 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.

239081

Q6R5P0

NP_991388

Mouse

Unconjugated

Primary Antibodies

Innate Immunity

TLR11 Antibody is Ion exchange chromatography purified.

Cat. No. 1283 - RAW 264.7 Cell Lysate

1 mg/mL

TLR11 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

TLR11 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

Tlr11

Cat. No. 17-203 - RAW 264.7 Cell Slide

Toll-like receptor 11

Mus musculus

Vogel SN, Fitzgerald KA, and Fenton MJ. TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. Mol. Interv. 2003; 3:466-77.

Takeda K, Kaisho T, and Akira S. Toll-like receptors. Annu. Rev. Immunol. 2003; 21:335-76.

Janeway CA Jr. and Medzhitov R. Innate immune recognition. Annu. Rev. Immunol. 2002; 20:197-216.

O'Neill LAJ, Fitzgerald FA, and Bowie AG. The Toll-IL-1 receptor adaptor family grows to five members. Trends in Imm. 2003; 24:286-9.

TLR11 Antibody: Gm287, Gm287, Toll-like receptor 11

ELISA, WB, ICC, IF

45429992

Liquid