TLR3 Polyklonale Antilichaam, PE-Cy5 Vervoeging

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response (By similarity) .

AI957183; Toll-like receptor 3; CD283; Tlr3

142980

Q99MB1

Cell membrane

Human, Mouse, Rat

801-905/905

TLR3

PE-Cy5

KLH conjugated synthetic peptide derived from mouse TLR3

WB, FCM

Purified by Protein A.

488nm/670nm

1µg/µl

WB (1:300-5000), FCM (1:20-100)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

142980

Dog, Pig