TM4SF2 (TSPAN7) (NM 004615) Humaan Recombinant eiwit

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked cognitive disability and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. [provided by RefSeq, Jul 2008]

Purified recombinant protein of Human tetraspanin 7 (TSPAN7), esidues 113-213aa, with C-terminal DDK tag, expressed in human cells.

A15; CCG-B7; CD231; DXS1692E; MRX58; MXS1; TALLA-1; TM4SF2; TM4SF2b

7102

P41732

NM_004615

Xp11.4

HEK293

C-DDK

>50 ug/mL as determined by microplate BCA method

> 90% as determined by SDS-PAGE and Coomassie blue staining

Liquid

PBS, pH7.4, 10% glycerol

Druggable Genome, Transmembrane

13.1 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

TSPAN7

Human

NP_004606

https://www.ncbi.nlm.nih.gov/gene/7102

https://www.uniprot.org/uniprot/P41732

https://www.ncbi.nlm.nih.gov/nuccore/NM_004615

https://www.ncbi.nlm.nih.gov/nuccore/NP_004606