TMEM106A Antilichaam

TMEM106A Antibody: Transmembrane protein 106A (TMEM106A) is a single-pass transmembrane protein that is closely related to TMEM106B, a protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual roles of TMEM106A and TMEM106B are still undetermined; however, as TMEM106B is involved in FTLD, it is possible that TMEM106A may also be a risk factor for FTLD.

113277

Q96A25

NP_659478

Human, Mouse

Unconjugated

Primary Antibodies

Neuroscience

TMEM106A Antibody is affinity chromatography purified via peptide column.

Cat. No. 1288 - A20 Cell Lysate

1 mg/mL

TMEM106A Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

TMEM106A antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

TMEM106A

Transmembrane protein 106A

Homo sapiens

Van Deerlin VM, Sleiman PM, Martinez-Lage M, et al. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat. Genet. 2010; 42:234-9

Aswathy PM, Jairani PS, and Mathuranath PS. Genetics of frontotemporal lobar degeneration. Ann. Indian Acad. Neurol. 2010; 13 (Suppl 2) :S55-62.

TMEM106A Antibody: Transmembrane protein 106A

ELISA, WB, IHC-P, IF

21450796

Liquid