TMEM135 Antilichaam

TMEM135 Antibody: The transmembrane protein 135 (TMEM135), also known as peroxisomal membrane protein 52 (PMP52), was initially identified as a protein that might be critical for adipogenesis and osteoblastogenesis. Further studies have indicated that TMEM135 may be part of a regulatory circuit that plays an important role in fat metabolism and energy expenditure in both C. elegans as well as mammalian organisms. Finally, recent experiments has suggested that TMEM135 may be an additional driver of breast cancer.

65084

Q86UB9

NP_075069

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Obesity

TMEM135 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1464 - Rat Liver Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (94%)

TMEM135 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

TMEM135 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

At least two isoforms of TMEM135 are known to exist; this antibody will detect both isoforms.

TMEM135

Cat. No. 10-201 - Human Liver Tissue Slide

Transmembrane protein 135

Homo sapiens

Scheideler M, Elabd C, Zaragosi LE, et al. Comparative transcriptomics of human multipotent stem cells during adipogenesis and osteoblastogenesis. BMC Genomics 2008; 9:340.

Exil VJ, Avila DS, Benedetto A, et al. Stress-induced TMEM135 protein is part of a conserved genetic network involved in fat storage and longetivity regulation in Caenorhabditis elegans. PLoS One 2010; 5:e14228.

Natrajan R, Mackay A, Lambros MB, et al. A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and –positive breast cancers. J. Pathol. 2012; 227:29-41.

TMEM135 Antibody: PMP52, Transmembrane protein 135, Peroxisomal membrane protein 52, PMP52

ELISA, WB, IHC-P, IF

281182571

Liquid