TMEM27 Antilichaam

This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells.

57393

Q9HBJ8

Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human TMEM27 (NP_065716.1) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

Mouse kidney

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 29kDa

IgG

WB: 1:500 - 1:2000

TMEM27

Mouse pancreas

Rat kidney

Collectrin, amino acid transport regulator

Homo sapiens

NX-17, NX17, TMEM27, collectrin, kidney-specific membrane protein, transmembrane protein 27

WB

Liquid