TMEM41B (CT) Antilichaam

TMEM41B Antibody: TMEM41B is required for autophagosome formation and participates in early stages of autophagosome biogenesis at the ER membrane probably via mobilization of neutral lipids from lipid droplets. TMRM41B is a critical host factor required for infection by human coronaviruses SARS-CoV-2, HCoV-OC43, HCoV-NL63, and HCoV-229E, as well as all flaviviruses tested such as Zika virus and Yellow fever virus. It is required post-entry of the virus to facilitate the ER membrane remodeling necessary to form replication organelles.

440026

Q5BJD5

Q5BJD5

Human, Mouse, Rat

9565

Unconjugated

Primary Antibodies

Infectious Disease, COVID-19

TMEM41B Antibody is affinity chromatography purified via peptide column.

Cat. No. 1405 – Mouse Kidney Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine (100%) ; Chicken (100%) ; Chimpanzee (100%) .

TMEM41B Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

TMEM41B antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

TMEM41B

Cat. No. 17-001 - HeLa Cell Slide

Transmembrane protein 41B

Homo sapiens

Moretti et al. EMBO Rep. 2018; 19 (9) :e45889.

Shoemaker et al. PLoS Biol. 2019; 17 (4) :e2007044.

Schneider et al. Cell 2021; 184 (1) :120-132.

Hoffmann et al. Cell 2021; 184 (1) :133-148.e20.

TMEM41B Antibody: Transmembrane protein 41B, Protein stasimon, TMEM41B, KIAA0033.

ELISA, IF, WB

74741383

Liquid