TMEM88 Antilichaam

TMEM88 Antibody: Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner.

92162

Q6PEY1

EAW90125

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Signal Transduction

TMEM88 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1303 - Human Brain Tissue Lysate

1 mg/mL

TMEM88 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

TMEM88 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

At least two isoforms of TMEM88 are known to exist; this antibody will recognize both isoforms.

TMEM88

Transmembrane protein 88

Homo sapiens

Lee HJ, Finklestein D, Li X, et al. Identification of transmembrane protein 88 (TMEM88) as a dishevelled-binding protein. J. Biol. Chem. 2010; 285:41549-56.

TMEM88 Antibody: TMEM88A, Transmembrane protein 88

ELISA, WB, IHC-P, IF

44662813

Liquid