TMIE Antilichaam

This gene encodes a transmembrane inner ear protein. Studies in mouse suggest that this gene is required for normal postnatal maturation of sensory hair cells in the cochlea, including correct development of stereocilia bundles. This gene is one of multiple genes responsible for recessive non-syndromic deafness (DFNB), also known as autosomal recessive nonsyndromic hearing loss (ARNSHL), the most common form of congenitally acquired inherited hearing impairment.

259236

Q8NEW7

Q8NEW7

Human, Mouse

This TMIE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the Central region of human TMIE.

Unconjugated

Primary Antibodies

Neuroscience

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

17 kDa

Rabbit Ig

For WB starting dilution is: 1:1000

TMIE

Transmembrane inner ear expressed protein

Homo sapiens

Yang, J.J., et al. Int. J. Pediatr. Otorhinolaryngol. (2010) In press

Sirmaci, A., et al. Clin. Genet. 75 (6) :562-567 (2009)

Santos, R.L., et al. J. Mol. Med. 84 (3) :226-231 (2006)

Cho, K.I., et al. Comp. Med. 53 (6) :642-648 (2003)

Transmembrane inner ear expressed protein, TMIE

WB

212276469

Liquid