Tn-antigeen
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Tn Antigen (Tn Epitope) (Compound 1) is a Trypanosoma cruzi trans-sialidase (TcTS) inhibitor with inhibition rate of 57% at 1 mM. Tn Antigen shows anti-trypanosomal activity with an IC50 of >0.5 mM. Tn Antigen can be used for the research of Chagas’ disease[1].
67262-86-6
GalNAcα-O-Ser
12352005
H302-H315-H319-H335
Parasite
Anti-infection
Infection
O[C@@H]([C@H]1O)[C@@H](NC(C)=O)[C@@H](OC[C@H](N)C(O)=O)O[C@@H]1CO
C11H20N2O8
308.29
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
[1]Martins-Teixeira MB, et al. α-Selective glycosylation affords mucin-related GalNAc amino acids and diketopiperazines active on Trypanosoma cruzi. Bioorg Med Chem. 2013 Apr 1;21 (7) :1978-87.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W040126/
Reference compound2
No Development Reported
Beschrijving
Tn Antigen (Tn Epitope) (Compound 1) is a Trypanosoma cruzi trans-sialidase (TcTS) inhibitor with inhibition rate of 57% at 1 mM. Tn Antigen shows anti-trypanos
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