TNF alfa Recombinant eiwit

TNF-alpha is a pleiotrophic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-alpha is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-alpha also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. Recombinant murine TNF-alpha is a soluble 156 amino acid protein (17.3 kDa) which corresponds to C-terminal extracellular domain of the full length transmembrane protein.

21926

P06804

NP_001265530.1

Recombinant Proteins

E. coli

Chemokines & Cytokines, Growth Factors, Immunology, Signal Transduction

Room Temp

The lyophilized TNF alpha recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted TNF alpha is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing TNF alpha recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Tumor necrosis factor

Mus musculus

DIF, Tnfa, TNF-a, TNFSF2, Tnfsf1a, TNFalpha, TNF-alpha, Tnfsf2, Tumor necrosis factor, Cachectin

Murine

518831589

Lyophilized