TNF-É Rabbit pAb (APR18490N)

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TNF-α Rabbit pAb (APR18488N4) .

TNF; DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F; TNF alpha

7124

P01375

Cell membrane, Membrane, Secreted, Single-pass type II membrane protein, Single-pass type II membrane protein

IHC (Mouse breast cancer, Homo sapiens, Mus musculus, Rattus norvegicus) ChIP (Homo sapiens, Mus musculus) IF (Rattus norvegicus, Homo sapiens, Mus musculus) WB (Homo sapiens, quails, Mus musculus, Rattus norvegicus, Gallus gallus)

WB 1:1000 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100

Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Calculated MW: 25kDa Observed MW: 28KDa

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7124

https://www.uniprot.org/uniprot/P01375

Email for sequence