TNFR1/TNFRSF1A Proteïne (C-His, Human)

TNFR1/TNFRSF1A

CD120a, FPF, MS5, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR1-d2, TNFR55, TNFR60, p55, p55-R, p60

P19438

C-His

Cell culture, ELISA

< 1.0 EU per μg of the protein as determined by the LAL method.

> 92 % as determined by reducing SDS-PAGE.

1. Immobilized human TNFRI-His at 10 μg/mL (100 μl/well) can bind biotinylated human TNFα. The EC50 of biotinylated human TNFα is 5-12 μg/mL. 2. Measured by its ability to inhibit TNFα-mediated cytotoxicity in L929 mouse fibrosarcoma cells in the presence of metabolic inhibitor actinomycin D. The ED50 for this effect is typically 0.2-1μg/mL in the presence of 0.25 ng/mL recombinant human TNFα.

Met 1-Thr 211

22.7 kDa

Human