TNFRSF11A Antilichaam

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.

8792

Q9Y6Q6

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 466-616 of human TNFRSF11A (NP_003830.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Innate Immunity, Signal Transduction

Affinity purification

HT-29

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 75kDa

IgG

TNFRSF11A

Mouse brain

Rat kidney

Tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Homo sapiens

TRANCE-R; TNFRSF11A; ODFR; CD265

WB, IHC, IF

Liquid