TNFRSF18 Antilichaam

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+) CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

8784

Q9Y5U5

Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 26-255 of human TNFRSF18 (NP_683699.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Innate Immunity, Signal Transduction

Affinity purification

Mouse thymus

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 30kDa

IgG

WB: 1:500 - 1:2000

TNFRSF18

Tumor necrosis factor receptor superfamily, member 18

Homo sapiens

TNFRSF18, AITR, GITR, CD357, GITR-D

WB

Liquid