TNFRSF18 Mouse Monoclonal Antibody [Kloon ID: UMLBI203]

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+) CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb

Carrier-free (BSA/glycerol-free) TNFRSF18/CD357 mouse monoclonal antibody, clone UMLBI203

AITR; CD357; GITR; GITR-D

Homo sapiens TNF receptor superfamily member 18 (TNFRSF18), transcript variant 1, mRNA.

8784

Q9Y5U5

Unconjugated

Cytokine-cytokine receptor interaction

Cytokine-cytokine receptor interaction

IHC 1:100~200

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Secreted Protein, Transmembrane

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

TNFRSF18

https://www.ncbi.nlm.nih.gov/gene/?term=8784

https://www.uniprot.org/uniprot/Q9Y5U5