TNFRSF1A Proteïne (C-human IgG1-Fc, Muis)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
TNFRSF1A
CD120a, FPF, p55, p55-R, TNF-alphaR1, TNF-R, TNF-R-I, TNF-R1, TNF-R55, TNFalpha-R1, TNFAR, Tnfr-1, Tnfr-2, Tnfr1, TNFR60, TNFRI, TNFRp55, Tnfrsf1a
• HEK 293
C-human IgG1-Fc
< 1.0 EU per μg of the protein as determined by the LAL method
> 90 % as determined by SDS-PAGE
1. Measured by its binding ability in a functional ELISA. Immobilized Mouse TNF-alpha (Cat:50349-MNAE) at 2 μg/ml (100 μl/well) can bind Mouse TNFRSF1AhFc (Cat:50496-M02H), the EC50 of Mouse TNFRSF1AhFc is 1.5-9.0 ng/mL. 2. Measured by its ability to inhibit the TNFα-mediated cytotoxicity in the L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 15-65 ng/mL in the presence of 0.1 ng/mL of recombinant mouse TNFα.
Met1-Ala212
The secreted recombinant mouse TNFRSF1A/Fc is a disulfide-linked homodimer. The reduced monomer consists of 424 amino acids and has a predicted molecular mass of 47.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm TNFRSF1A/Fc monomer is approximately 55 kDa due to glycosylation.
Mouse
Beschrijving
TNFRSF1A Proteïne (C-human IgG1-Fc, Muis) Beschikbaar in 100 µg. Bestel eenvoudig online met snelle levering.
Specificaties
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