TNFRSF4 Antilichaam - middengebied: HRP (ARP59086 P050-HRP)

Tumor necrosis factor receptor superfamily, member 4

OX40, ACT35, CD134, IMD16, TXGP1L

7293

P43489

NP_003318

Human, Pig

The immunogen is a synthetic peptide directed towards the middle region of human TNFRSF4

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.

TRAF4; TRAF5; TRAF3; TRAF2; TRAF1; TNFRSF9; SIVA1; TNFSF4

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

TNFRSF4 is strongly supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Human: 100%; Pig: 86%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

27kDa

Wet Ice

277

TNFRSF4

TNFRSF4

Rabbit

Tumor necrosis factor receptor superfamily member 4

NM_003327

GKHTLQPASNSSDAICEDRDPPATQPQETQGPPARPITVQPTEAWPRTSQ