TNFSF9 Antilichaam - C-terminalgebied: FITC (ARP61434 P050-FITC)

Tumor necrosis factor (ligand) superfamily, member 9

CD137L, TNLG5A, 4-1BB-L

8744

P41273

NP_003802

Human

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.

TIRAP; TLR4; IRAK2; UBC; TNFRSF9; TRAF2; TRAF1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB, IHC

Affinity Purified

0.5 mg/ml

Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

28kDa

Wet Ice

254

TNFSF9

TNFSF9

Rabbit

Tumor necrosis factor ligand superfamily member 9

NM_003811

SVSLALHLQPLRSAAGAAALALTVDLPPASSEARNSAFGFQGRLLHLSAG