TNIP1 Polyklonale Antilichaam

Abin-1 is a 636 amino acid protein that localizes to both the nucleus and the cytoplasm and is shuttled between the two intercellular regions in a CRM1-dependent manner. Expressed ubiquitously with highest expression in spleen and skeletal muscle, Abin-1 interacts with A20 and, via this interaction, interferes with TRAF2-mediated transactivation signals and effectively inhibits TNF-induced NF_B expression. Additionally, Abin-1 can be incorporated into HIV-1 virions and, if overexpressed, can inhibit viral replication. Abin-1 may also play an important role in the regulation of nuclear import and export activities. Multiple isoforms of Abin-1 exist due to alternative splicing events.

ABIN 1; ABIN-1; abin1; HIV-1 Nef interacting protein Nip40-1; TNFAIP3 interacting protein 1; HIV-1 Nef interacting protein; HIV-1 Nef-interacting protein; hVAN; KIAA0113; NAF 1; NAF-1; NAF1; Nef-associated factor 1; Nef-associated factor 1 SNP; Nip 40-1; Nip40-1; TNFAIP3 interacting protein 1; TNFAIP3-interacting protein 1; TNIP 1; TNIP-1; Tnip1; TNIP1_HUMAN; VAN; Virion associated nuclear shuttling protein; Virion-associated nuclear shuttling protein.

Rat

351-450/636

TNIP1

Unconjugated

KLH conjugated synthetic peptide derived from human TNIP1

WB, IHC-P, IF (IHC-P)

Purified by Protein A.

1µg/µl

WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Human, Mouse, Dog, Cow, Pig, Horse, Rabbit