TNKS1BP1 Antilichaam - middengebied: Biotine (ARP58347_P050-Biotine)

Tankyrase 1 binding protein 1, 182kDa

TAB182

85456

Q9C0C2

NP_203754

Human

The immunogen is a synthetic peptide directed towards the middle region of human TNKS1BP1

TNKS-1 mRNA in urine sediment from patients with bladder TCC correlated with tumor stage, and higher preoperative levels were associated with increased risk of early recurrence. Tankyrase-1 is required in the assembly of bipolar spindles and the spindle-pole protein NuMA as a substrate for covalent modification by tankyrase-1. Data also show that tankyrase 1 inhibition in human cancer cells enhances telomere shortening by a telomerase inhibitor and hastens cell death.

UBC; RNF219; SPC25; RABGEF1; DCTN3; SPTBN1; NLK; CSNK2A1; CNOT6L; CNOT6; VCP; HNRNPK; DYNC1H1; CBX3; SIRT7; TSG101; Cnot3; Capza1; TNKS2; TNKS

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

190kDa

Gelmini, S., (2007) Clin. Chem. Lab. Med. 45 (7), 862-866

Wet Ice

1729

TNKS1BP1

TNKS1BP1

Rabbit

182 kDa tankyrase-1-binding protein

NM_033396

DGEASQTEDVDGTWGSSAARWSDQGPAQTSRRPSQGPPARSPSQDFSFIE