ToAP2 (TFA)

ToAP2 TFA is a potent antimicrobial peptide. ToAP2 TFA affects C. albicans membrane permeability and produces changes in fungal cell morphology[1].

12352209

Antibiotic; Fungal

Anti-infection

COVID-19-immunoregulation

Infection

O=C(N[C@@H](CC1=CC=CC=C1)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(N3[C@@H](CCC3)C(NCC(N[C@@H](C(C)C)C(N[C@@H](CCSC)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC5=CC=CC=C5)N.O=C(C(F)(F)F)O.[x]

C144H235N35O32S.xC2HF3O2

3000.69 (free base)

[1]do Nascimento Dias J, et al. Mechanisms of action of antimicrobial peptides ToAP2 and NDBP-5.7 against Candida albicans planktonic and biofilm cells. Sci Rep. 2020 Jun 25;10 (1) :10327.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P11021A/

Peptides

No Development Reported