Tofacitinib-d3
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Tofacitinib-d3 (Tasocitinib-d3) is deuterium labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.
Tasocitinib-d3; CP-690550-d3
12352005
Isotope-Labeled Compounds
Others
COVID-19-immunoregulation
Inflammation/Immunology; Cancer
O=C(N1C[C@@H]([C@@H](CC1)C)N(C([2H])([2H])[2H])C2=C3C(NC=C3)=NC=N2)CC#N
C16H17D3N6O
315.39
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-40354S5/
Isotope-Labeled Compounds
No Development Reported
Beschrijving
Tofacitinib-d3 (Tasocitinib-d3) is deuterium labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respect
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