Tolcapon
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Catechol O-methyltransferase inhibitor (COMT), inhibiting both brain and peripheral enzymes.1 Potent inhibitor of alpha-synuclein and beta-amyloid oligomerization and fibrillogenesis protecting against extracellular toxicity.2 Binds to transthyretin (TTR) with high affinity (21 to 58 nM) and inhibits TTR aggregation in human plasma and prevents TTR-induced cytotoxicity in vitro. Stabilizes TTR in mice and humans in vivo.3 Inhibits O-methylation of exogenous polyphenols such as EGCG.4 Cell permeable. Orally bioavailable
Unconjugated
Yellow solid
-20°C
Beschrijving
Tolcapon Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
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