Toruleen

Torulene (Torulin) is an orally active carotenoid with anti-cancer activity. Torulene inhibits proliferation and induces apoptosis of tumor cells via a mitochondrial signal pathway and the down-regulation of androgen receptor (AR) expression. Torulene can be used for the study of prostate cancer[1][2].

547-23-9

Torulin

12352211

Androgen Receptor; Apoptosis; Bcl-2 Family; MMP

Apoptosis; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Cancer-Kinase/protease

Cancer

C/C(C)=C/C=C/C(C)=C/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C

C40H54

534.86

[1]Du C, et al. The suppression of torulene and torularhodin treatment on the growth of PC-3 xenograft prostate tumors. Biochem Biophys Res Commun. 2016 Jan 22;469 (4) :1146-52.|[2]Chao Du, et al. The suppression of torulene and torularhodin treatment on the growth of PC-3 xenograft prostate tumors, Biochemical and Biophysical Research Communications, Volume 469, Issue 4,2016, Pages 1146-1152, ISSN 0006-291X

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N15686/

Natural Products

No Development Reported