TP53 neoepitope
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
TP53 neoepitope is a high-affinity antigenic peptide targeting HLA-A. TP53 neoepitope can triggers CD8+ T cell-mediated killing of TP53-mutant tumor cells. TP53 neoepitope is promising for research of solid tumors harboring TP53 hotspot mutations (e.g., R175H, R273H) [1].
151808-74-1
12352209
MHC
Immunology/Inflammation
Cancer
O=C(N[C@@H](CCSC)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CS)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC2=CNC=N2)N
C45H74N16O13S2
1111.30
[1]Gurung HR, et al. Systematic discovery of neoepitope-HLA pairs for neoantigens shared among patients and tumor types. Nat Biotechnol. 2024 Jul;42 (7) :1107-1117.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P11089/
Peptides
No Development Reported
Beschrijving
TP53 neoepitope is a high-affinity antigenic peptide targeting HLA-A. TP53 neoepitope can triggers CD8+ T cell-mediated killing of TP53-mutant tumor cells. TP53
Specificaties
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