TPR Antibody - C-terminal regio : HRP (ARP61102 P050-HRP)

Translocated promoter region, nuclear basket protein

7175

P12270

NP_003283

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human TPR

This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs) . The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.

STAU1; UBC; LGR4; MDM2; MAD1L1; EED; NPM1; LMNA; HDAC9; ITGA4; FN1; CBX7; BUD31; TAF15; TOP1; SNRPD1; SNRPA1; SRSF5; SFPQ; S100A9; RPL37A; RPL18A; RPL6; RBM4; RAN; PRKDC; NHP2L1; SEPT2; IK; HRAS; HNRNPU; HNRNPA2B1; EEF1D; EEF1B2; DDX3X; DDX1; DDB1; CIRBP

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB, IHC

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

267kDa

Wet Ice

2363

TPR

TPR

Rabbit

Nucleoprotein TPR

NM_003292

SSEAGLEIDSQQEEEPVQASDESDLPSTSQDPPSSSSVDTSSSQPKPFRR