
TQB-2858
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
TQB-2858 is a bifunctional fusion protein composed of a monoclonal antibody against PD-L1 fused with the extracellular domain of TGF-β receptor. TQB-2858 has a high affinity for PD-L1, TGF-β1, and TGF-β3 and exhibited high PD-L1 target occupancy. TQB-2858 can be used for the study of osteosarcoma and alveolar soft part sarcoma (ASPS) [1].
12352203
PD-1/PD-L1
Immunology/Inflammation
Cancer-programmed cell death
Cancer
[1]Xie L, et al. Exploratory study of an anti-PD-L1/TGF-β antibody, TQB2858, in patients with refractory or recurrent osteosarcoma and alveolar soft part sarcoma: a report from Chinese sarcoma study group (TQB2858-Ib-02) . BMC Cancer. 2023 Sep 15;23 (1) :868.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991084/
Inhibitory Antibodies
Phase 2
Beschrijving
TQB-2858 is a bifunctional fusion protein composed of a monoclonal antibody against PD-L1 fused with the extracellular domain of TGF-β receptor. TQB-2858 has a
Specificaties
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